Serial Amnioreduction to Treat TTTS

Serial amnioreduction is a less invasive approach in managing the symptoms of Twin to Twin Transfusion Syndrome (TTTS).

This procedure involves the removal of the excess fluid from around the recipient twin with a needle, similar to an amniocentesis.

This is a temporizing measure, but not curative. It will reduce the amount of fluid around the recipient twin and temporarily alleviate some associated pain and pressure.

Typically, amnioreduction is repeated multiple times over the course of the pregnancy as the fluid tends to re-accumulate.

This technique is often recommended for milder cases of Twin to Twin Transfusion Syndrome or cases occurring after 26 weeks of pregnancy, but it is generally not effective for severe Twin to Twin Transfusion Syndrome.

Results for Serial Amnioreduction

Results for serial amnioreduction are:

  • 40-60% survival rate of at least one twin
  • Approximately 25% of the surviving twin suffers some brain damage

Referral for Serial Amnioreduction

If you are interested in a referral for serial amnioreduction, either you or your provider can contact our program coordinator:

Melissa Dorn, RN, MN
Fetal Therapy Coordinator 
1.866.FETSURG (toll free)