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KARMET

Objective

Investigational Drug Study for Patients with Parkinson’s Disease-Related Constipation

Booth Gardner Parkinson’s Care Center is conducting a study to evaluate the safety, tolerability and effectiveness of repeated oral doses of an investigational drug for up to 25 days in patients with Parkinson’s Disease-related constipation.

Who may be eligible to participate?

Subjects 30-to-90 years of age with a diagnosis of Parkinson's Disease (defined as the presence of at least three of the following cardinal features: rest tremor, rigidity, bradykinesia and/or akinesia, postural and gait abnormalities) and constipation (which has been present for over 6 months and is unresponsive to first line, typically over the counter treatments).

Other inclusion/exclusion criteria apply.

What does participation involve?

The study will be conducted on an outpatient basis. Patients will be randomized 1:1 to treatment or placebo.

Each patient will have six visits to the clinic:

  • a screening visit
  • a randomization visit
  • three follow up visits
  • one end of study visit
Investigator

Daniel Burdick, MD, Booth Gardner Parkinson’s Care Center

Clinical Trial Categories

  • Parkinson's Disease
Contact
EvergreenHealth Research Services at 425-899-5385
or EvergreenResearch@evergreenhealth.com

Contact Us

Call us at (425) 899-5385 or use our online information request form.

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