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Adaptive COVID-19 Treatment Trial 4 (ACTT-4), NIH


Goal: To evaluate the clinical efficacy of baricitinib + remdesivir versus dexamethasone + remdesivir as assessed by the mechanical ventilation free survival by Day 29.

  • Phase III, randomized, double-blind, placebo-controlled trial.
  • Subjects will be assessed daily while hospitalized. If the subjects are discharged from the hospital, they will have a study visit at Days 15, 22, and 29.
  • Multicenter trial with 100 centers globally and 1500 subject enrollment goal.

Diego Lopez de Castilla, MD, EvergreenHealth Infectious Disease Care

Clinical Trial Categories

  • COVID-19
EvergreenHealth Research Services at 425-899-5385