Essential Tremor with Uncontrollable Hand Movement Trial


The goal of this study is to assess the safety & effectiveness of a new wrist device worn to ease common symptoms of essential tremor over a three-month period, particularly uncontrollable hand movement. The device is called Cala TWO, and is worn on the wrist, much like a fitness tracker bracelet.


Am I eligible to participate?

Eligible participants will meet the following criteria at minimum. However, we encourage you to connect with our research team to determine whether this trial is a fit for you, and to explore other trial opportunities that may align with your health goals and care plan.

  • Age 22 or older
  • Hand tremors due to essential tremor
  • Moderate to severe hand tremors in the dominant hand
  • No implanted electrical medical device, such as a pacemaker, defibrillator, or deep brain stimulator
  • No previous brain surgery for the treatment of tremor
  • No suspected or diagnosed epilepsy or other seizure disorder
  • No implanted metal in your dominant wrist
  • No nerve problems affecting the dominant hand
  • No other neurodegenerative disease (e.g. Parkinson’s, Alzheimer’s, etc.)
  • No Botox for hand tremor within 6months prior to study entry
  • No participation in another interventional clinical trial within 30days of study entry
  • Not pregnant or anticipating pregnancy during the course of the study
  • No diagnosed alcoholism

What does participation involve?

Participants will:

  • Attend three office visits, each lasting between 1-3 hours
  • Receive two scheduled phone call check-ins from your site’s study staff
  • Use the study device (an investigational, body-worn device) at home for three months to see if it may help with your hand tremor symptoms
  • Participants will be compensated for their time

Trial Investigator:  Pinky Agarwal, MD 

If you’re interested in enrolling, please submit this brief form, and a member of our research team will contact you.

You’re also welcome to contact the research team directly at 425.899.5385 or EvergreenResearch@evergreenhealth.com. We look forward to discussing your participation and answering your questions.

Learn more about research at EvergreenHealth

See all current Essential Tremor Trials

Directions to EvergreenHealth Research Services