Cardiology Clinical Trials

Comparison of Continuous Sternal ECG Patch Monitors (Carnation and Zio) Trial Identifier: NCT02952781

The purpose of this research is to compare the CarnationTM Ambulatory Monitoring (CAM) System and the Zio-XT iRhythm, which represents the current standard for continuous recording of the ECG over extended periods.

Who may be eligible to participate?
Subjects 18 years of age or older with one or more of the following:

  • Syncope of uncertain etiology; or
  • Pre-syncope of uncertain etiology; or
  • Palpitations of uncertain etiology; or
  • Management of known AF/SVT patients

Investigators: Mark Vossler, MD and Robert Rho, MD

For More Information: Karrie McLendon 425.899.0555 

UNTOUCHED identifier: NCT02433379

Understanding Outcomes With the EMBLEM™ S-ICD in Primary Prevention Patients With Low Ejection Fraction

This study assesses the 18-month incidence of all-cause shocks in subjects implanted with the EMBLEM Subcutaneous Implantable Defibrillator (S-ICD) for primary prevention of sudden cardiac death. Devices are to be programmed with zone cutoffs at 200 bpm and 250 bmp in order to mimic the programming settings for transvenous ICDs in the MADIT RIT study. The incidence of all-cause S-ICD shocks will be compared to the incidence of all-cause shocks observed in the MADIT RIT study.

Who may be eligible to participate?
Subjects 21 and older with ischemic or non-ischemic heart disease who meet current guidelines for ICD therapy and intends to undergo an implant procedure for an EMBLEM S-ICD (or newer generation BSC S-ICD).

Investigator: Edward Kim, MD

For More Information: Shalom Kilcup 425.899.5369